ORGANIC CHEMISTRY

课程简介

/ Indicative Syllabus Alkanes, Alkenes, Alkynes and Aromatic Compounds Structures, reactivity and properties; conformation of alkanes and cycloalkanes; addition reactions; mechanism, stereochemistry and regioselectivity; hydration; halogenation; hydrohalogenation; hydrogenation; hydroxylation; epoxidation; hydroboration; electrophilic aromatic substitution reactions; Friedel-Crafts reactions; substituent effects in electrophilic aromatic substitution; mechanism; nitration; sulphonation. Stereochemistry Structural parameters and strains; stereoisomerism-configuration and conformation; chirality, enantiomerism, sigma- and pi-diastereomerism. -- 1 of 3 -- Spectral Analysis of Functional Groups Basic principles and uses of mass spectrometry, infrared, ultraviolet-visible and 1H nuclear magnetic resonance spectroscopies in the identification of functional groups of simple organic compounds. Alkyl Halides Structure of alkyl halides; preparation of alkyl halides; nucleophilic substitution reactions; elimination reactions; mechanism and stereochemistry; regioselectivity; factors affecting nucleophilic substitution and elimination reactions: molecular structure, solvent, nucleophile, leaving group and neighbouring group. Alcohols, Phenols, Ethers and Thiols Structure, reactivity and preparation; hydrogen bonding; acidity; dehydration; oxidation. Aldehydes and Ketones Structure, properties and reactions; oxidation; nucleophilic addition reactions; hydration; acetal formation; imine formation; alcohol formation. Carboxylic Acids and Derivatives Classification, reactivity and preparation; acidity of carboxylic acids; nucleophilic acyl substitution reactions. Amines and Heterocyclic Amines Structure, properties and preparation; basicity of amines; acylation.

目标

The aim of this subject is to enable students to understand organic chemistry through a study of the basic reaction types, the basic principles and the uses of common spectroscopic techniques available for functional group identification. Emphasis will be placed on reactions and compounds with structural interest as well as biological and industrial importance. This subject will be supplemented by practicals to equip students with the basic skills and techniques in organic chemistry.

先修要求

General Chemistry I Co-requisite None

Teaching Pattern

Methodology Lectures will be used to provide fundamental principles and concepts of different topics in organic chemistry including chemical functional groups, chemical reactivity, chemical reactions, reaction mechanisms and spectroscopic analysis of organic compounds in organic chemistry. Tutorials are designed to assist students to consolidate their learned concepts, to improve their problem- solving skills and to stimulate their further interest in the subject. Laboratory experiments will be performed by students to improve their understanding of the principles and to develop their ability to observe and analyze as well as their practical proficiency and teamwork capability.