ORGANIC CHEMISTRY I

课程简介

/ Indicative Syllabus Alkanes, Alkenes, Alkynes and Aromatic Compounds Structures, reactivity and properties; conformation of alkanes and cycloalkanes; addition reactions; mechanism, stereochemistry and regioselectivity; hydration; halogenation; hydrohalogenation; hydrogenation; hydroxylation; epoxidation; hydroboration; electrophilic aromatic substitution reactions; Friedel-Crafts reactions; substituent effects in electrophilic aromatic substitution; mechanism; nitration; sulphonation. Stereochemistry Structural parameters and strains; stereoisomerism-configuration and conformation; chirality, enantiomerism, and diastereomerism. Spectral Analysis of Functional Groups Basic principles and uses of mass spectrometry, infrared, ultraviolet-visible and 1 H nuclear magnetic resonance spectroscopies in the identification of functional groups of simple organic compounds. Alkyl Halides Structure of alkyl halides; preparation of alkyl halides; nucleophilic substitution reactions; elimination reactions; mechanism and stereochemistry; regioselectivity; factors affecting nucleophilic substitution and elimination reactions: molecular structure, solvent, nucleophile, leaving group and neighbouring group. Alcohols, Phenols, Ethers and Epoxides Structure, reactivity and preparation; hydrogen bonding; acidity; dehydration; -- 1 of 3 -- oxidation. Aldehydes and Ketones Structure, properties and reactions; oxidation; nucleophilic addition reactions; hydration; acetal formation; imine formation; alcohol formation. Carboxylic Acids and Derivatives Classification, reactivity and preparation; acidity of carboxylic acids; nucleophilic acyl substitution reactions.

目标

The aim of this subject is to enable students to understand organic chemistry through a study of the basic reaction types, the basic principles and the uses of common spectroscopic techniques available for functional group identification. Emphasis will be placed on reactions and compounds with structural interest as well as biological and industrial importance.

先修要求

ABCT1741 General Chemistry I

Teaching Pattern

Methodology Lectures will be used to provide fundamental principles and concepts of different topics in organic chemistry including chemical functional groups, chemical reactivity, chemical reactions, reaction mechanisms and spectroscopic analysis of organic compounds in organic chemistry. Tutorials are designed to assist students to consolidate their learned concepts, to improve their problem-solving skills and to stimulate their further interest in the subject.