Advanced Analytical Techniques

课程简介

/ Indicative Syllabus Mass Spectrometry Basic concepts: isotope, mass, resolution, mass accuracy, nitrogen rule, etc.; ionization techniques: electron ionization, chemical ionization, fast atom bombardment, electrospray, MALDI, etc.; mass analysers: magnetic sector, TOF, quadrupole, quadrupole ion trap, FT-ICR, etc.; MS/MS; GC/MS and LC/MS; ICP-MS; qualitative and quantitative applications. Advanced Separation Techniques Principles and applications of supercritical fluid chromatography, capillary electrophoresis, etc. Advanced Imaging Techniques Working principles and applications of scanning microscopy and atomic force microscopy. Rapid Analytical Techniques Structural and binding properties of antibodies; structural and catalytic properties of enzymes; antibody-antigen and enzyme-substrate interactions; enzyme linked immunosorbent assay (ELISA); radioimmunoassy (RIA); immunosensors; biosensors; fundamental principles and instrumentation of the systems; measurement techniques and result interpretations

目标

This subject provides students with background theory and applications of selected and current topics in advanced analytical techniques for chemical and biological analysis. These techniques are applicable to inorganic, organic, biological, industrial and environmental analysis.

先修要求

Analytical Chemistry II or Analytical Spectroscopy

Teaching Pattern

Methodology Lecture: basic principles will be introduced and discussed. Examples will be used to illustrate the applications of various techniques. Tutorials: a set of tutorial problems will be given to allow students to apply the knowledge acquired from the lecture. Students are encouraged to solve the problems before seeking assistance. These will help students consolidate what they have learned and develop a deeper understanding of the subject. -- 1 of 2 --